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HomeBiz NewsThe evolving impact of Chronic Kidney Disease in a crisis-hit Sri Lanka

The evolving impact of Chronic Kidney Disease in a crisis-hit Sri Lanka

By Dr. Malith Atapattu

Chronic kidney disease (CKD) is quickly becoming a major public health concern, attracting increased global attention because of the disease’s rapid rate of incidence and its grave impact on patients and their quality of life. In Sri Lanka alone, there are over 164,000 identified CKD patients today, with another staggering 11,000 annually diagnosed with the condition, and 10,500 eventually succumbing to the complications caused by it.

So what is CKD and how does it come about? Essentially, CKD is the slow, progressive and irreversible loss of kidney function over several years, to a point that brings about kidney failure. Over time, the condition damages the routine functionalities of a kidney, obstructing its ability to filter waste and fluid, and allowing harmful waste to build up to such an extent that it harms a person’s health and wellbeing. It is usually caused by other secondary conditions that put a strain on the kidneys, and is often the result of a combination of different problems such as high blood pressure, diabetes, high cholesterol, kidney infections, polycystic kidney disease, kidney stones, and even the long-term use of certain medicines.

In CKD stages one to three, which are mild to moderate stages of the condition, patients are generally unlikely to feel unwell or present symptoms. However, even at this point, CKD can be diagnosed by an estimated glomerular filtration rate (eGFR) before any symptoms develop.

Once a patient is diagnosed, the psychosocial toll it creates amplifies due to the physical discomfort of the illness as well as treatment modalities such as oral medications, hemodialysis, renal transplantation, dietary, and fluid restrictions. Depending on the stage a patient is in, other stressors may include financial burden of dialysis, high time commitment for dialysis, a feeling of worthlessness and a burden to loved ones, a fear of pain through treatment, low sleep cycles, eating restrictions, and the constant worry of how all this impacts their families. In fact, these mental stressors are not limited to the patient, their immediate communities and loved ones are also affected by the massive commitment of frequent treatment that CKD creates.

Symptoms start to present strongly when the kidney damage starts becoming more fierce – stage 4 or worse. If kidney function continues to gradually decline then various other problems may develop – for example, anaemia and an imbalance of calcium, phosphate and other chemicals in the bloodstream. These can cause various symptoms, such as tiredness due to anaemia, and bone thinning or fractures due to calcium and phosphate imbalance.

Eventually, end-stage kidney failure, stage 5, can prove to be fatal unless treated quickly and efficiently.

While the incidence of CKD elevates with age, the incidence of Chronic Kidney Disease of Uknown Origin (CKDu) depends on a multitude of environmental factors. CKDu tends to affect rural populations with limited access to safe drinking water and affects men more than women. In many patients, CKDu will progress to end-stage renal disease, which might be catastrophic for individuals in poor areas and communities where access to renal replacement therapy is limited or not affordable.

While there is no cure for chronic kidney disease, treatment can slow or halt the progression of the disease and can prevent other serious conditions from developing because of it. To survive end-stage kidney disease, the individual may need to have artificial kidney treatment, either through dialysis or with a kidney transplant to maintain their quality of life and health, with both procedures placing an intense level of financial burden on Sri Lankan patients and their loved ones.

Dialysis is one of the primary methods of treating CKD. It is a procedure to remove waste products and excess fluid from the blood when the kidneys stop working properly, and often involves diverting blood to a machine to be cleaned. In Sri Lanka, only 74 dialysis centers are currently available to cater to the frequent, island-wide demand of 164,000 patients, through just 482 machines.

With catastrophic numbers such as these, the national healthcare system often finds it difficult to cater to the full requirement of all patients requiring dialysis, affecting their health and wellbeing to a large degree. Further, in Sri Lanka where the worsening macroeconomic conditions have put a gigantic strain on the healthcare supply chain, an increasing number of CKD patients continue to be impacted negatively, with strain on both their health and the wellbeing of their loved ones and communities.  

In such a dire context, it has then become critical for the private healthcare sector to step up to the plate to elevate their support to ensure that all CKD patients in Sri Lanka have a fair and equal chance at a good life with access to the treatments and medication they need to survive and thrive.

[The writer is Dr. Malith Atapattu, Head of Medical Services – Hemas Hospitals]

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6 COMMENTS

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    References:

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  2. In contrast, Xyosted and different T injections
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  3. Un professionnel peut vous conseiller sur
    la nécessité d’un test sanguin et d’autres vérifications
    pertinentes. Il est essentiel d’agir rapidement pour
    éviter que les effets négatifs des niveaux bas de testostérone ne s’aggravent avec le temps.
    Manque de libido, fatigue anormale, troubles de la focus…
    Dans certains cas, ces symptômes peuvent indiquer un manque de testostérone chez l’homme.
    Le level avec le Dr Jean-Michel Lecerf, médecin nutritionniste,
    spécialiste en endocrinologie et maladies métaboliques. Il n’est
    jamais trop tard pour prendre en primary son propre taux de testostérone.

    En outre, des mesures ciblées telles que la prise de zinc ou d’ashwagandha peuvent également stimuler le taux de testostérone.

    La plupart du temps, elle est administrée par voie orale,
    mais elle existe également en application topique.

    En plus de réduire le nombre de poussées de lupus,
    une supplémentation améliore la qualité
    de vie des personnes, en ce qui concerne le bien-être psychological et la sexualité.

    Ainsi, elle peut être proposée aux femmes atteintes
    de Lupus en situation de détresse mentale et / ou de sexualité altérée
    57‌. Les personnes souffrant d’insuffisance surrénalienne ou ayant subi l’ablation des
    surrénales ne la produisent pas. Les traitements, à base de cortisone (glucocorticoïdes de synthèse), peuvent
    empêcher la manufacturing naturelle de cette hormone par les surrénales.

    Des anomalies dans le rapport DHEA/cortisol sont observées chez les personnes
    présentant des troubles psychiques.
    « Il n’a jamais été démontré que son utilisation augmentait le taux de testostérone chez l’Homme »,
    assure-t-elle. Par ailleurs, l’excès de graisse, en particulier autour de la taille, est souvent associé à
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    Si vous hésitez sur la conduite à tenir après avoir omis une dose, demandez conseil à votre médecin ou à un pharmacien. Avant d’utiliser ce médicament,
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    l’accompagnent. Si vous êtes incertain de la façon d’utiliser le produit ou si vous avez des questions à
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    divers noms de marque ou sous différentes présentations.
    Cependant, la taurine utilisée dans les compléments
    alimentaires et les vitality drinks est synthétisée en laboratoire.

    L’humeur aqueuse traverse la pupille et remplit la chambre antérieure de l’œil (l’espace entre l’iris et la cornée).
    Vous ne pouvez pas constater par vous-même que vous souffrez d’hypertension oculaire, car il n’y a aucun signe
    extérieur comme une douleur oculaire ou des yeux rouges.
    Oui, il est recommandé d’être à jeun eight à 12 heures avant la prise de
    sang pour des résultats précis. Elle se fait généralement le matin, à jeun, par une easy prise de sang au niveau du bras.
    Rassurez-vous, suite à sa prescription, votre médecin vous aidera à interpréter le résultat de votre prise de sang.
    Les diff�rents dosages de testost�rone dans
    le sang au cours de votre traitement par FORTIGEL, devront �tre
    pratiqu�s par le m�me laboratoire automotive les valeurs analytiques
    peuvent varier d�un laboratoire d�analyse � un autre.
    Deux semaines apr�s le d�but de votre traitement,
    votre m�decin proc�dera � des prises de sang afin de v�rifier si votre dose doit �tre modifi�e ou non.
    Attention, la testostérone en excess ou les hormones anabolisantes peuvent nuire.
    Mieux vaut choisir des moyens naturels pour augmenter sa testostérone.
    Ça inclut la bonne nourriture, le sommeil, le sport et la gestion du stress.
    Il est important de bien s’entraîner et de manger équilibré pour profiter
    de la testostérone.
    Elle contrôle aussi la libido et participe au développement
    des organes sexuels masculins. Le manque d’hormone mâle est généralement associé à des
    conséquences désagréables pour les hommes.

    Ils n’aiment pas en parler publiquement, ainsi que du fait même du traitement.

    On notera que dans les deux cas, une supplémentation est utile
    en cas de déficience. Une modification significative de la
    focus plasmatique de testostérone ne se produit qu’au 2ème jour du
    traitement. Pour cette raison, l’ajustement de la dose doit être effectué au plus
    tôt le 3e jour de la prise du médicament. La dose quotidienne commonplace
    est de 50 mg de principe actif, ce organe qui produit la testostéRone – skilled-moms.com
    – correspond à 1 sachet (5 g).

  4. In order to understand why this examine is essential, let’s discuss how Are steroids Bad for
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    Sometimes, we examine labs about every six months till we find the best regimen for you.

    An necessary caveat is that many of those adjustments are irreversible – should
    you cease taking testosterone, some of the bodily modifications will not go
    away. And in case you are one of the tiny minority that adjustments their thoughts about transitioning, you will not
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    to extend your pure testosterone output. To help trans adolescents, oestrogen and testosterone may
    be used to induce physical changes that higher align with their gender.
    Rachel Skinner receives funding from the National Health and Medical Research Council’s Medical Analysis Future
    Fund and the Australian Analysis Council for related
    analysis. She is an adolescent medication paediatrician employed by the
    Sydney Kids’s Hospitals Community and provides medical care to trans younger individuals.
    To support trans adolescents, estrogen and testosterone may
    be used to induce bodily adjustments that higher align with their gender.

    Of course, whenever you inject may depend in your private dosage, focus,
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    Many men new to testosterone therapy could also be curious
    in regards to the differences between injecting in the morning,
    or later at night time earlier than mattress. Testosterone degree,
    hematocrit, and the number of patients withpolycythemia in numerous upkeep testosterone dosages.
    You’re also avoiding the mental nervousness that
    often accompanies feeling unstable. If you realize that your finest emotions will soon be adopted by uneasy
    intervals, it may possibly get to your head.
    Microdosing can also enhance the conversion of testosterone
    to DHT, a potent type of testosterone. Lastly, for these switching over from a previous
    supplier to FOLX for GAHT/HRT care, we will settle for labs drawn throughout the last yr, as
    long as they have been accomplished whereas on the identical route and dosage requested from
    FOLX.
    If you’re a cis girl on testosterone HRT, testosterone can also help you
    handle painful durations. In addition, many different parameters are concerned in precisely determining the worth of testosterone injections.
    Past that, the value of testosterone injections differ, typically by a lot,
    as a end result of a quantity of different causes. There are several brands of
    injectable testosterone that are legally available for sale in the US, and their costs do
    range based on pharmaceutical manufacturer. For many trans males, hormone therapy in the form of testosterone
    is a vital and often needed step in their gender transition.
    Again, whether or not an individual has functioning ovaries may
    play a component in the outcomes, as will general health.
    Many feel more emotionally balanced and at residence of their bodies with a maintenance level of testosterone.
    Finally, for some men, testosterone is an integral a
    part of their male id. DISCLAIMER The info contained
    herein is for use for educational purposes solely.

    The author isn’t a medical professional, and this data should not be thought-about medical recommendation. This info ought to NOT be used to switch consultation with or
    treatment by a skilled medical skilled. The listing of a medicine herein does not suggest endorsement by the author.

    Be certain to specific any considerations you might need to your healthcare provider–you may simply need to regulate your
    dosage. If you need assistance to search out one, see our guide for locating
    a trans-friendly healthcare supplier. The preliminary dosage and frequency of the injections are determined by
    the prescribing healthcare skilled based mostly on the person’s hormone ranges and overall well being.
    During the initial phase of hormone remedy, a decrease dosage could additionally be administered to allow the body to regulate gradually.

    Over time, the dosage could also be gradually increased to achieve desired results.

    It is possible that you might have heard some horror tales
    concerning withdrawal signs from stopping testosterone alternative therapy,
    or that serious unwanted effects can happen once you stop taking testosterone.
    Most of these tales are rumors, and the results of misinformation, and people who have misused
    or abused testosterone. It is true that your physique can have withdrawal-like signs
    when you cease taking testosterone. Nevertheless, such adverse impacts of stopping testosterone nearly all the time happen if you stop all of a sudden, with out your doctor’s authorization. It
    isn’t a good suggestion beneath any circumstances to stop “cold turkey.” If you’re feeling you’re experiencing unwanted
    facet effects, or not getting the results you need, from your testosterone therapy, do
    not simply cease. Monitoring hormone ranges helps make positive that the
    testosterone dose is appropriate for your wants.
    Younger individuals might require a decrease dosage
    and less frequent administration, as their bodies are nonetheless growing.
    On the opposite hand, older individuals may require higher dosages and extra frequent administration, as their hormone levels may be naturally lower because of aging.
    Testosterone within the type of injections is the most common technique for
    transgender males.
    The testosterone that’s used for masculinizing hormone therapy is identical to the hormone that the testicles and ovaries make naturally.
    Do Not use synthetic androgens, such as oral methyl testosterone or anabolic steroids.
    It’s unclear whether masculinizing hormone therapy raises the danger of ovarian and uterine cancer.

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    extract. Most of the components are well-dosed in accordance with scientific trials.
    Extra cortisol, a stress hormone, can injury muscle tissue and
    make it tougher to do workout routines.
    But as with any product, I wanted to do Steroids Make you Lose weight my analysis before incorporating it into my routine.
    That’s after I stumbled upon reviews on Six Star Testosterone Booster.

    From glowing suggestions to cautionary tales, these evaluations present useful perception into the effectiveness and potential unwanted aspect effects of this
    popular supplement. Join me as we delve into the world
    of testosterone boosters and uncover what these
    critiques should say about Six Star Testosterone Booster.
    Before diving into the review, let’s first understand what exactly is 6 Star Testosterone
    Booster.
    Those unwanted facet effects could be the result of sudden fluctuations or too many highs and lows.
    The different unfavorable of the Six Star testosterone booster is the dearth of estrogen blockers.
    But since it wasn’t overly potent on the T-count aspect, that might not be a real problem.
    That’s in all probability why you’ll discover
    a lot of articles about its obvious impression on testosterone manufacturing.

    Rhodiola Extract 386mg – There’s probably some profit to this, though current studies are inconclusive and only present very minimal testosterone features as in comparability with a placebo.

    [2] Rhodiola rosea seems to have a more pronounced effect on cortisol, which does decrease testosterone, however except you’re at present under high stress it will not probably do
    something. The one optimistic thing we can say about pro vitamin six star testosterone booster is that at least this is inside the efficient dosage vary.

    [4] That’s not to say it will not do anything at all, however considering this is as
    close to getting something right as they come, it is not nice.
    Six star testosterone booster got here close to getting one thing proper right here.

    When his outcomes got here again that it didn’t
    appear to extend energetic free testosterone levels, he
    switched to a unique product. The study confirmed that the group
    who acquired the complement got to take care of peak testosterone to
    cortisol ratio. One examine did some in depth testing on efficiency
    ranges in athletes in a double-blind placebo trial [3].
    But the fascinating thing wasn’t a boosted testosterone manufacturing
    throughout the physique.

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